How the Ancient Viral DNA in Our Genome Affects Disease and Development
Human endogenous retroviruses make up 8 percent of the human genome. Researchers are studying how active they are
Gene therapy: How can poorer countries access the most expensive drugs in the world?
https://www.weforum.org/agenda/2022/10/gene-therapies-hiv-cancer-uganda/
Study reports blocking key enzyme boosts anti-cancer T-cell responses and resistance to immunosuppression
https://www.sciencedaily.com/releases/2022/08/220829112853.htm
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses
https://www.frontiersin.org/articles/10.3389/fimmu.2022.987298/full
The Effect of Glucose on Rapid Cancer Cell Proliferation & Waste
An Examination of the Anti-Cancer Properties of Plant Cannabinoids in Preclinical Models of Mesothelioma
https://www.mdpi.com/2072-6694/14/15/3813
Doctors may have found a secret weapon to fight cancer: Viagra
Doctors may have found a secret weapon to fight cancer: Viagra
Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts
https://www.sciencedirect.com/science/article/pii/S2666379122000416
Nivolumab Plus Ipilimumab Vs. Chemotherapy: Survival Outcome
Blue-Green Algae Could Help Treat Cancer And Alzheimer’s Disease
A dog parasite could help fight incurable cancers—what our immunotherapy research revealed
https://medicalxpress.com/news/2022-10-dog-parasite-incurable-cancerswhat-immunotherapy.html
Cholesterol-lowering drug tested for effect on prostate cancer tumors
Synergistic Anti-tumor Effect of Dichloroacetate and Ivermectin
We formerly reported that the combination of dichloroacetate, omeprazole, and tamoxifen blocked cancer progression by reducing lactic acid production and inducing superoxide production. Recently, ivermectin, a well-known anti-parasite drug, was reported to share the same mechanisms with them and have anti-tumor activity. Here, we present three patients in whom the combination of dichloroacetate, omeprazole (plus tamoxifen), and ivermectin dramatically relieved the symptoms accompanying cancer and sarcoma progression.
Anticancer, antioxidant, antiviral and antimicrobial activities of Kei Apple (Dovyalis caffra) fruit
https://www.nature.com/articles/s41598-022-09993-1
Anti-cancer effects of fenbendazole on 5-fluorouracil-resistant colorectal cancer cells
https://www.kjpp.net/journal/view.html?doi=10.4196/kjpp.2022.26.5.377
Fenbendazole induces cell cycle arrest in colorectal cancer cells and patient-derived colon cancer organoids
https://aacrjournals.org/cancerres/article/82/12_Supplement/2313/701049
Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer
https://www.sciencedirect.com/science/article/abs/pii/S0024320522002363
Cyclodextrin Dispersion of Mebendazole and Flubendazole Improves In Vitro Antiproliferative Activity
https://www.mdpi.com/2227-9717/9/12/2185
Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors
https://www.mdpi.com/2072-6694/14/14/3368
Flubendazole Plays an Important Anti-Tumor Role in Different Types of Cancers
https://www.mdpi.com/1422-0067/23/1/519
Chemokines and their Receptors: Multifaceted Roles in Cancer Progression and Potential Value as Cancer Prognostic Markers
https://www.mdpi.com/2072-6694/12/2/287
Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684115/
IVC Protocol – Vitamin-C
https://riordanclinic.org/research-study/vitamin-c-research-ivc-protocol/
Vitamin E δ-tocotrienol sensitizes human pancreatic cancer cells to TRAIL-induced apoptosis through proteasome-mediated down-regulation of c-FLIPs
https://cancerci.biomedcentral.com/articles/10.1186/s12935-019-0876-0
Effects of fenbendazole and vitamin E succinate on the growth and survival of prostate cancer cells
Anti-inflammatory ω-3 endocannabinoid epoxides
https://www.pnas.org/doi/full/10.1073/pnas.1610325114
Scientists discover slug that can decapitate itself, grow new body
The bizarre discovery could pave the way for advances in regenerative medicine for humans.
https://www.freethink.com/science/sea-slug-regenerative-medicine
Cannabigerolic acid, a major biosynthetic precursor molecule in cannabis, exhibits divergent effects on seizures in mouse models of epilepsy
https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15661
The NALCN channel regulates metastasis and nonmalignant cell dissemination
https://www.nature.com/articles/s41588-022-01182-0
The Race to Make a Vaccine for Breast Cancer
https://time.com/6220114/breast-cancer-vaccine-development/
Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
https://www.cell.com/cell/fulltext/S0092-8674(22)01127-8
Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568762/
NAD+ Helps Natural Killer Cells to Fight Cancer
Cancer fighting requires cellular energy.
https://www.lifespan.io/news/nad-helps-natural-killer-cells-to-fight-cancer/
Losartan – Study reveals how to activate the immune system’s natural killer cells to protect against cancer and other diseases
https://www.sciencedaily.com/releases/2022/03/220316145739.htm
https://www.science.org/doi/10.1126/sciadv.abk3327
Peritoneal restoration by repurposing vitamin D inhibits ovarian cancer dissemination via blockade of the TGF-β1/thrombospondin-1 axis
https://www.sciencedirect.com/science/article/pii/S0945053X22000397
https://reader.elsevier.com/reader/sd/pii/S0945053X22000397
Creating MHC-restricted neoantigens with covalent inhibitors that can be targeted by immune therapy
New Research: Tumor Cells Can Manipulate the Body’s Natural Antibody Response to Triple Negative Breast Cancer
Scientists find the cause of severe COVID symptoms
Anticancer effects of herbal medicines in pancreatic ductal adenocarcinoma through modulation of steroid hormone response proteins
https://www.nature.com/articles/s41598-022-14174-1
A lymphatic-absorbed multi-targeted kinase inhibitor for myelofibrosis therapy
https://www.nature.com/articles/s41467-022-32486-8
Nivolumab Plus Ipilimumab Vs. Chemotherapy: Survival Outcome
Efficacy of metformin therapy in patients with cancer: a meta-analysis of 22 randomised controlled trials
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02599-4
FDA Approves New Immunotherapy Combination To Treat Advanced Liver Cancer
https://www.mskcc.org/news/fda-approves-new-immunotherapy-combination-treat-advanced-liver
Fasting inhibits aerobic glycolysis and proliferation in colorectal cancer via the Fdft1-mediated AKT/mTOR/HIF1α pathway suppression
https://www.nature.com/articles/s41467-020-15795-8
Compound in pomegranates may help fight colon cancer