Articles and science papers (unsorted part 2.4)

Dipyridamole – Blood thinner’s ability to boost fat burning could inspire new obesity therapies

https://www.fiercebiotech.com/research/blood-thinners-ability-boost-fat-burning-could-inspire-new-obesity-therapies

https://www.nature.com/articles/s41586-022-05041-0

Mysterious ‘Russian Flu’ 130 Years Ago May Have Been a Coronavirus, Scientists Say

https://www.sciencealert.com/scientists-are-wondering-if-the-1889-russian-flu-was-actually-caused-by-coronavirus

106-million-year-old virus found ‘fossilised’ in the human genome

The remnants of a virus that plagued our mammal ancestors during the age of the dinosaurs have been found lurking in our genomes

https://www.newscientist.com/article/2308806-106-million-year-old-virus-found-fossilised-in-the-human-genome/

The crucial connection between gut bacteria and Covid-19 symptoms, explained

Is this why some people develop a severe disease while others don’t?

https://www.inverse.com/innovation/gut-bacteria-covid

Magnesium may prime the immune system to fight cancer and infections

https://www.medicalnewstoday.com/articles/magnesium-may-prime-the-immune-system-to-fight-cancer-and-infections

In Wildnis fast ausgestorben Mexikanische Aktivisten feiern Aufzucht wilder Axolotl

Axolotl sind auf mehrere Weisen besondere Amphibien: Neben ihren Fähigkeiten der Regeneration sind sie nur in wenigen Seen rund um Mexiko-Stadt zu finden. Die Anzahl der in freier Wildbahn lebenden Axolotl ist in den letzten Jahren stetig geschrumpft. Nun feiern Wildschützer einen Teilerfolg.

https://www.n-tv.de/mediathek/videos/panorama/Aufzucht-wilder-Axolotl-in-Mexiko-Aktivisten-feiern-Teilerfolg-article23135080.html

Astonishing Discovery Shows Humpback Whales Swimming Thousands of Miles to Mate

https://www.sciencealert.com/humpback-whales-have-been-spotted-crossing-the-ocean-for-good-sex

Breakthrough Research Finds Link Between ‘Long COVID’ And Vagus Nerve Damage

https://www.zerohedge.com/covid-19/breakthrough-research-finds-link-between-long-covid-and-vagus-nerve-damage

Psilocybin Treatment for Major Depression Effective for up to a Year for Most Patients

A “Striking” Link Between Vitamin D Levels and Omicron

Low levels are associated with the severity of Omicron and other variants.

https://www.psychologytoday.com/us/blog/the-fallible-mind/202202/striking-link-between-vitamin-d-levels-and-omicron

The Biggest Galaxy Ever Found Has Just Been Discovered, And It Will Break Your Brain

https://www.sciencealert.com/at-over-16-million-light-years-across-this-is-the-biggest-galaxy-ever-discovered

Innate Immune Suppression by SARS-CoV-2 mRNA Vaccinations: The role of G-quadruplexes, exosomes and microRNAs

https://www.researchgate.net/publication/357994624_Innate_Immune_Suppression_by_SARS-CoV-2_mRNA_Vaccinations_The_role_of_G-quadruplexes_exosomes_and_microRNAs

Regular use of ivermectin as prophylaxis for COVID-19 led up to 92% reduction in COVID-19 mortality rate in a dose-response manner: results of a prospective observational study of a strictly controlled population of 88,012 subjects among 223,128 participants.

https://www.researchgate.net/publication/358386329_Regular_use_of_ivermectin_as_prophylaxis_for_COVID-19_led_up_to_92_reduction_in_COVID-19_mortality_rate_in_a_dose-response_manner_results_of_a_prospective_observational_study_of_a_strictly_controlled_

Resistenzen sorgen für erschütternd viele Todesfälle

Zu den häufigsten Todesursachen weltweit gehören Infektionen mit antibiotikaresistenten Bakterien. Allein wegen Escherichia coli starben im Jahr 2019 rund 200 000 Menschen.

https://www.spektrum.de/news/bakterien-antibiotikaresistenz-fuehrt-zu-erschuetternd-vielen-toten/1986235

Innate Immune Suppression by SARS-CoV-2 mRNA Vaccinations: The role of G-quadruplexes, exosomes and microRNAs

https://www.authorea.com/doi/full/10.22541/au.164276411.10570847

Anti-aging mechanism of calorie restriction identified in Yale study

https://newatlas.com/health-wellbeing/yale-calorie-restriction-reverse-immune-aging/

WUHAN-THEORIE: Worauf stützen Sie Ihre Verschwörungsvorwürfe, Prof. Wiesendanger?

What Really Happened In Wuhan: A Virus Like No Other, Countless Infections, Millions

https://www.scribd.com/audiobook/521910099/What-Really-Happened-In-Wuhan-A-Virus-Like-No-Other-Countless-Infections-Millions-of-Deaths

Researchers find anti-cancer activity in marine seagrass

https://www.thehindu.com/news/national/tamil-nadu/researchers-find-anti-cancer-activity-in-marine-seagrass/article38305709.ece

Metabolism found to regulate production of killer cells

https://phys.org/news/2022-02-metabolism-production-killer-cells.html

‘Biggest breakthrough’ in pancreatic cancer care as scientists discover potential CURE

https://www.thesun.co.uk/health/17573479/breakthrough-pancreatic-cancer-care-scientists/

Vitamin D Deficiency Linked to Severe COVID

https://www.medscape.com/viewarticle/968121

A Common Over-The-Counter Drug Could Treat Long COVID, Case Study Reports

The patient now takes 25 mg of diphenhydramine at night and 180 mg fexofenadine in the morning, and says she feels 95 percent better.

https://www.sciencealert.com/there-s-evidence-antihistamines-may-help-treat-long-covid-symptoms

Changing Your Diet Can Add Up to 10 Years to Your Life Expectancy, New Study Shows

https://www.sciencealert.com/new-research-suggests-that-changing-your-diet-could-add-a-decade-to-your-life

Highly Virulent HIV Variant Discovered in the Netherlands

https://www.medscape.co.uk/viewarticle/highly-virulent-hiv-variant-discovered-netherlands-2022a1000aft

“… Ivermectin showed the best result against Omicron.”

Insights from a computational analysis of the SARS-CoV-2 Omicron variant: Host-pathogen interaction, pathogenicity and possible therapeutics

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9210926/

Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity

https://www.nature.com/articles/s41551-021-00831-9

Origanum majorana harvested from Al-Soda, Saudi Arabia promotes mitotic arrest and apoptosis in colon cancer cells

https://www.sciencedirect.com/science/article/pii/S1018364722000593

The Natural Chemotherapeutic Capsaicin Activates AMPK through LKB1 Kinase and TRPV1 Receptors in Prostate Cancer Cells

https://www.mdpi.com/1999-4923/14/2/329

Chemical characterization of non-psychoactive Cannabis sativa L. extracts, in vitro antiproliferative activity and induction of apoptosis in chronic myelogenous leukaemia cancer cells

https://onlinelibrary.wiley.com/doi/full/10.1002/ptr.7357

Antihistamines may impact response to immune checkpoint inhibitors for cancer

https://www.healio.com/news/hematology-oncology/20220208/antihistamines-may-impact-response-to-immune-checkpoint-inhibitors-for-cancer

Harnessing the Herpes Virus to Beat a Deadly Brain Cancer

https://consumer.healthday.com/2-8-harnessing-the-herpes-virus-to-beat-a-deadly-brain-cancer-2656526180.html

Colorectal cancers raise defensive barrier in response to chemotherapy

https://medicalxpress.com/news/2022-02-colorectal-cancers-defensive-barrier-response.html

Anticancer Drug Shrinks Tumors in Almost a Third of Patients in Recurrent Glioblastoma Trial

https://www.technologynetworks.com/cancer-research/news/anticancer-drug-shrinks-tumors-in-almost-a-third-of-patients-in-recurrent-glioblastoma-trial-358249

Widely available supplement may explain brain boost from exercise

Studies in mice show selenium increases the number of new neurons, and improves memory in old age

https://www.science.org/content/article/widely-available-supplement-may-explain-brain-boost-exercise

Common pain killer could increase heart disease and strokes in some people

Non-invasive Method to Deliver Drugs to the Brain

Gut Microbes Can Cause Obesity, And We’re Getting Closer to Understanding How

https://www.sciencealert.com/scientists-discover-how-some-gut-microbiomes-could-be-promoting-obesity

Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle

https://www.nature.com/articles/s41401-021-00752-y

An overview of the anti-SARS-CoV-2 properties of Artemisia annua, its antiviral action, protein-associated mechanisms, and repurposing for COVID-19 treatment

https://www.sciencedirect.com/science/article/pii/S2095496421000637

Photosensitization of a subcutaneous tumour by the natural anthraquinone parietin and blue light

https://www.nature.com/articles/s41598-021-03339-z

RHUBARB can save your life: Ingredient in plant kills half of cancer cells in 48 hours

https://www.express.co.uk/life-style/health/613194/Cancer-killing-drug-rhubarb-ready-within-years

A Brazilian berry may hold the key to cancer treatment

https://www.trtworld.com/life/a-brazilian-berry-may-hold-the-key-to-cancer-treatment-54429

New Link Between Gut Microbiome & Lethal Prostate Cancer

https://journals.lww.com/oncology-times/fulltext/2022/02050/new_link_between_gut_microbiome___lethal_prostate.7.aspx

Israeli study offers strongest proof yet of vitamin D’s power to fight COVID

https://www.timesofisrael.com/israeli-study-offers-strongest-proof-yet-of-vitamin-ds-power-to-fight-covid/

Has The Red Carpet Been Rolled Out For A Mainstream Pivot On Ivermectin?

https://www.zerohedge.com/markets/has-red-carpet-been-rolled-out-mainstream-pivot-ivermectin

Fasting-Mimicking Diet Is Safe and Reshapes Metabolism and Antitumor Immunity in Patients with Cancer

https://aacrjournals.org/cancerdiscovery/article/12/1/90/675618/Fasting-Mimicking-Diet-Is-Safe-and-Reshapes

A faulty immune response may be behind lingering brain trouble after COVID-19

Headaches and trouble thinking plague some people after a coronavirus infection

Scientists Regrow Frogs’ Lost Legs. Will Human Limbs Be Next?

https://www.medscape.com/viewarticle/967784

Why the COVID death rate in the U.S. is so much higher than other wealthy nations

Researchers discover how lactic acid weakens anti-tumor defenses

Immune cells feed on lactic acid and paralyze other ‘killer’ immune cells

https://www.sciencedaily.com/releases/2022/01/220128141333.htm

https://www.cell.com/cell-reports/fulltext/S2211-1247(21)01671-5

Hyaluronic acid fuels pancreatic cancer cell growth

https://elifesciences.org/articles/62645

Identification of foods that affect the anti‑cancer activity of pitavastatin in cells

https://www.spandidos-publications.com/10.3892/ol.2022.13193

Gut bacteria may play a role in the development of long COVID

https://www.medicalnewstoday.com/articles/gut-bacteria-may-play-a-role-in-the-development-of-long-covid

This Breakthrough Cancer Treatment Has Prevented Leukemia Relapse for Over a Decade

https://www.thedailybeast.com/car-t-cell-therapy-prevented-leukemia-cancer-remission-in-patients-for-over-10-years

Compound in the Herb Rosemary May Be Useful Against COVID-19 and Other Inflammatory Diseases

Ivermectin Has ‘Antiviral Effect’ Against Omicron And All Other ‘Mutant Strains’ Of Covid-19

https://www.zerohedge.com/covid-19/ivermectin-has-antiviral-effect-against-omicron-and-all-other-mutant-strains-covid-19

Ivermectin shows ‘antiviral effect’ against COVID, Japanese company says

https://www.reuters.com/business/healthcare-pharmaceuticals/japans-kowa-says-ivermectin-effective-against-omicron-phase-iii-trial-2022-01-31/

Wissenschaftler fordern Antworten von BionTech: Was ist da eigentlich drin und wie sichert ihr die Qualität?

Meditation reorganizes the brain’s spatial topography

Meditators invert the relationship between the layers of self-processing.

A new meta-analysis examined evidence of how meditation alters brain activity and connectivity. The authors found that meditation reorganizes the brain’s spatial topography. Perhaps this explains why advanced meditators claim to experience “non-dual awareness” — that is, a dissolution of the boundaries between the self and the environment, resulting in a state of unity with the world.

https://bigthink.com/neuropsych/meditation-change-brain-spatial-topography/

Ursolic and oleanolic acids in combination therapy inhibit migration of colon cancer cells through down-regulation of the uPA/uPAR-dependent MMPs pathway

https://www.sciencedirect.com/science/article/pii/S0009279722004070

Metformin – Common diabetes drug may help reverse liver inflammation

Unique gut bacteria could be responsible for triggering rheumatoid arthritis in at-risk people

https://www.news-medical.net/news/20221026/Unique-gut-bacteria-could-could-be-responsible-for-triggering-rheumatoid-arthritis-in-at-risk-people.aspx

Elevated Immune Response to Gut Bacterial Protein Associated with Rheumatoid Arthritis

https://www.rheumatologynetwork.com/view/elevated-immune-response-to-gut-bacterial-protein-associated-with-rheumatoid-arthritis

Sapanisertib – Cancer drug could potentially be used against malaria

https://phys.org/news/2022-10-cancer-drug-potentially-malaria.html

A global epidemic of cancer among people younger than 50 could be emerging

https://edition.cnn.com/2022/10/14/health/early-onset-cancer-increase/index.html

Common painkillers may harm heart, kidneys, bodyweight, and sleep

GABA – Scientists find inexpensive, readily available drug that may treat COVID-19

NAD+ Helps Natural Killer Cells to Fight Cancer

Cancer fighting requires cellular energy.

https://www.lifespan.io/news/nad-helps-natural-killer-cells-to-fight-cancer/

Olive Oil Is a Natural Cancer-Fighting Food, Daily Intake May Reduce Risk of Death

https://www.theepochtimes.com/health/study-olive-oil-is-a-natural-cancer-fighting-food-daily-intake-may-reduce-risk-of-death_4808700.html

Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4568762/

Newly discovered species of bacteria in the microbiome may be a culprit behind rheumatoid arthritis

https://theconversation.com/newly-discovered-species-of-bacteria-in-the-microbiome-may-be-a-culprit-behind-rheumatoid-arthritis-193267

Overcoming resistance to colon cancer treatment

https://www.sciencedaily.com/releases/2022/10/221027093324.htm

FOLFOXIRI Resistance Induction and Characterization in Human Colorectal Cancer Cells

https://www.mdpi.com/2072-6694/14/19/4812

The co-evolution of the genome and epigenome in colorectal cancer

https://www.nature.com/articles/s41586-022-05202-1

Study reveals how naturally-occurring compound kills major drug-resistant bacteria

https://phys.org/news/2022-10-reveals-naturally-occurring-compound-major-drug-resistant.html

Devil’s Club Falcarinol-Type Polyacetylenes Inhibit Pancreatic Cancer Cell Proliferation

https://www.tandfonline.com/doi/abs/10.1080/01635581.2018.1559931

Spermidine fights cancer

Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice

https://www.science.org/doi/10.1126/science.abj3510

Dietary Polyacetylenic Oxylipins Falcarinol and Falcarindiol Prevent Inflammation and Colorectal Neoplastic Transformation: A Mechanistic and Dose-Response Study in A Rat Model

https://www.mdpi.com/2072-6643/11/9/2223

Simvastatin Inhibits Endometrial Cancer Malignant Behaviors by Suppressing RAS/Mitogen-Activated Protein Kinase (MAPK) Pathway-Mediated Reactive Oxygen Species (ROS) and Ferroptosis

https://pubmed.ncbi.nlm.nih.gov/36276874/

Chemokines and their Receptors: Multifaceted Roles in Cancer Progression and Potential Value as Cancer Prognostic Markers

https://www.mdpi.com/2072-6694/12/2/287

EMT, cancer stem cells and autophagy; The three main axes of metastasis

https://www.sciencedirect.com/science/article/pii/S075333222031101X

Magic Traditional Chinese Medicine Ingredients Generated Autophagic Flux to Suppress Tumor Progression and Novel Combination Therapy Strategy in Gastric Cancer

https://www.newswise.com/articles/magic-traditional-chinese-medicine-ingredients-generated-autophagic-flux-to-suppress-tumor-progression-and-novel-combination-therapy-strategy-in-gastric-cancer

Piceatannol enhances Beclin-1 activity to suppress tumor progression and its combination therapy strategy with everolimus in gastric cancer

https://link.springer.com/article/10.1007/s11427-022-2185-9

The Therapeutic Potential of Piceatannol, a Natural Stilbene, in Metabolic Diseases

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444415/

Protein Pilfered from Cancer Cells Thwarts Immune Attack

New research in mice reveals why natural killer cells, normally effective at hunting cancer, are sometimes stopped in their tracks.

https://www.the-scientist.com/news-opinion/why-chomping-on-cancer-cells-can-thwart-immune-cells-attack-69908

Lapacho bark – Scientists Turn Brazilian Tree Bark Into Promising Treatment for Leukemia

Common cholesterol-lowering drug may lower COVID-19 severity, death risk

How an experimental treatment beat a little girl’s cancer

Emily Whitehead has a secret weapon: “My T-cells, part of my immune system, were trained to fight and kill my cancer.” She was only six when she became the first child ever to receive genetically-modified T cells. The experimental treatment cured her leukemia. https://www.cbsnews.com/news/how-an-experimental-treatment-beat-cancer-genetically-modified-car-t-cells/

These DNA-Damaging Molecules May Be The Link Between Colon Cancer And IBD

https://www.sciencealert.com/these-dna-damaging-molecules-may-be-the-link-between-colon-cancer-and-ibd

Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites

https://www.science.org/doi/10.1126/science.abm3233

Bird appears to set non-stop distance record with 8,435-mile flight from Alaska to Australia

https://www.cbsnews.com/news/bar-tailed-godwit-bird-non-stop-distance-record-8435-mile-flight-alaska-to-australia/

COVID-19 virus is becoming less severe, study finds

Autophagy Heals Damage from Spike Protein, Doctor Says

https://www.theepochtimes.com/health/autophagy-heals-damage-from-spike-protein-doctor-says_4824563.html

How Genes Can Leap From Snakes to Frogs in Madagascar

The discovery of a hot spot for horizontal gene transfer draws attention to the possible roles of parasites and ecology in such changes.

https://www.quantamagazine.org/how-genes-can-leap-from-snakes-to-frogs-20221027/

Major breakthrough in cancer research: Papers reveal ‘dark matter’ that contributes to disease’s growth

https://interestingengineering.com/health/breakthrough-cancer-research-dark-matter

Spermidine activates mitochondrial trifunctional protein and improves antitumor immunity in mice

https://www.science.org/doi/10.1126/science.abj3510

New Analysis of 845 COVID Jab-Related Leukemia Cases Sheds More Light on Post-Jab Cancer Uptick Warnings

https://www.theepochtimes.com/new-analysis-of-845-covid-jab-related-leukemia-cases-sheds-more-light-on-post-jab-cancer-uptick-warnings_4548528.html

Stanford study finds drug that prevents kidney failure in diabetes

EMT, cancer stem cells and autophagy; The three main axes of metastasis

https://www.sciencedirect.com/science/article/pii/S075333222031101X

New Hybrid Virus Discovered as Flu And RSV Fuse Into Single Pathogen

https://www.sciencealert.com/new-hybrid-virus-discovered-as-flu-and-rsv-fuse-into-single-pathogen

PEA – Palmitoylethanolamide Reduces Colon Cancer Cell Proliferation and Migration, Influences Tumor Cell Cycle and Exerts In Vivo Chemopreventive Effects

https://www.mdpi.com/2072-6694/13/8/1923/htm

Scientists find an important cause for chronic inflammation

Molecular structure of important receptors in immune system unravelled

https://www.siasat.com/molecular-structure-of-important-receptors-in-immune-system-unravelled-researchers-2438892/