Curcumin inhibits spike protein of new SARS-CoV-2 variant of concern (VOC) Omicron
https://www.sciencedirect.com/science/article/pii/S0010482522003444
Ceylon cinnamon and its major compound Cinnamaldehyde can limit overshooting inflammatory signaling and angiogenesis in vitro: implications for COVID-19 treatment
https://www.biorxiv.org/content/10.1101/2021.06.16.448642v1.abstract
The Original Antigenic Sin: How the vaccines might be making COVID-19 worse
Follow Your Nose: A Key Clue to Understanding and Treating COVID-19
https://www.frontiersin.org/articles/10.3389/fendo.2021.747744/full
Novel Immune Cell Population May Trigger Inflammation in Multiple Sclerosis and Other Brain Disorders
Getting exposed to another coronavirus can help you fight COVID-19, study says
https://www.deseret.com/coronavirus/2021/11/27/22798426/coronavirus-exposure-fight-covid-19-study
Cancer cells resist chemotherapy by helping their neighbors cheat death
https://medicalxpress.com/news/2021-11-cancer-cells-resist-chemotherapy-neighbors.html
Research Says GABA Supplement Is Also a Good Sleep Aid
B3 – Popular ‘anti-aging’ supplement may lead to brain cancer
B3 – Popular ‘anti-aging’ supplement may lead to brain cancer
Vaccine shown to prolong life of patients with aggressive brain cancer
Trial results suggest people with newly diagnosed glioblastoma could potentially be given extra years of life
Unusual Type of Antibody Shows Ultrapotent Activity Against Zika
Acute and postacute sequelae associated with SARS-CoV-2 reinfection
https://www.nature.com/articles/s41591-022-02051-3
Novel cancer-killing drug type harnesses the immune system
https://www.pnas.org/post/journal-club/cancer-killing-drug-strategy-harnesses-immune-system
Intravenous delivery may improve nanoparticle vaccine efficacy
2 diseases, one drug: How a drug for deadly cancer could treat COVID-19
Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations
https://www.sciencedirect.com/science/article/pii/S147655862200063X
Chinese Herbal Medicine Can Significantly Improve Anti-Cancer Treatment
Bojungikki-Tang Improves Response to PD-L1 Immunotherapy by Regulating the Tumor Microenvironment in MC38 Tumor-Bearing Mice
https://www.frontiersin.org/articles/10.3389/fphar.2022.901563/full
Chinese Red Dates: An Ancient Cancer Fighter
This delicious superfood has a long history in Chinese medicine
https://www.theepochtimes.com/health/chinese-red-dates-an-ancient-cancer-fighter_4636650.html
Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production
https://pubs.rsc.org/en/content/articlelanding/2018/fo/c8fo00526e
https://www.ebay.de/itm/284790015687
Ancient Chinese medicine unlocks new possibilities for cancer treatment
After 20 years of research, Yale pharmacologist Yung-Chi Cheng and his partners are launching the first international clinical trial for a botanical drug.
licorice, skullcap, peony, and dates
The botanical drug YIV-906 (center) is developed from an 1800-year-old Chinese formula and relies on four naturally derived ingredients: licorice, skullcap, peony, and dates.
https://news.yale.edu/2020/03/13/ancient-chinese-medicine-unlocks-new-possibilities-cancer-treatment
Cancer Drug Derived From Himalayan ‘Caterpillar Fungus’ Smashes Early Clinical Trial
Metabolic Reprogramming of Chemoresistant Cancer Cells and the Potential Significance of Metabolic Regulation in the Reversal of Cancer Chemoresistance
https://www.mdpi.com/2218-1989/10/7/289
The exercise pill: How exercise keeps your brain healthy and protects it against depression and anxiety
CAR-T Therapy May Treat Conditions Other Than Blood Cancers, Research Shows
https://www.verywellhealth.com/car-t-treatment-whats-next-6830735
Understanding the types of leukemia
Common and rare types of blood cancer
https://www.medicalnewstoday.com/articles/types-of-blood-cancer
Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
https://www.cell.com/cancer-cell/fulltext/S1535-6108(22)00378-6
letrozole – Could a repurposed drug break a centurylong stalemate in the war on cancer?
Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP
https://link.springer.com/article/10.1007/s11033-022-08072-y
Antitumor Activity of Simvastatin in Preclinical Models of Mantle Cell Lymphoma
https://www.mdpi.com/2072-6694/14/22/5601
Statins inhibit proliferation and induce apoptosis in triple-negative breast cancer cells
https://link.springer.com/article/10.1007/s12032-022-01733-9
Repurposed Itraconazole for use in the treatment of malignancies as a promising therapeutic strategy
https://www.sciencedirect.com/science/article/pii/S0753332222010058
Repurposing antifungal drugs for cancer therapy
https://www.sciencedirect.com/science/article/pii/S2090123222001990
Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner
https://synapse.koreamed.org/articles/1516079962
Anti-cancer effects of fenbendazole on 5-fluorouracil-resistant colorectal cancer cells
https://synapse.koreamed.org/articles/1516079963
Cancer Neuroscience: Evidence for a New Hallmark of Cancer
https://onlinelibrary.wiley.com/doi/full/10.1002/adbi.202200192
Repurposing of metabolic drugs and mitochondrial modulators as an emerging class of cancer therapeutics with a special focus on breast cancer
https://www.sciencedirect.com/science/article/pii/S2667394022000399
GABAergic signaling beyond synapses: an emerging target for cancer therapy
https://www.sciencedirect.com/science/article/abs/pii/S0962892422001957
Disulfiram loaded calcium phosphate nanoparticles for enhanced cancer immunotherapy
https://www.sciencedirect.com/science/article/abs/pii/S0142961222005208
Metabolic reprogramming in high-grade sarcomas: repurposing anti-cholesterol agents as a novel therapeutic strategy
https://aacrjournals.org/clincancerres/article/28/18_Supplement/B014/708884
The effect of flubendazole on microtubule polymerization and post-translational modifications
https://www.annalsofoncology.org/article/S0923-7534(22)04079-0/fulltext
Antidepressant Drug Sertraline against Human Cancer Cells
https://www.mdpi.com/2218-273X/12/10/1513
Metformin and bladder cancer: Drug repurposing as a potential tool for novel therapy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666131/
Statins as Repurposed Drugs in Gynecological Cancer
https://www.mdpi.com/1422-0067/23/22/13937
Clinically Relevant Statin-drug Combinations to Potentiate Breast Cancer Cell Death
https://tspace.library.utoronto.ca/handle/1807/125148
Venetoclax – Targeting notch signaling pathway in breast cancer stem cells through drug repurposing approach
https://link.springer.com/article/10.1007/s11030-022-10561-y
Novel molecular imaging radiotracer can precisely diagnose multiple cancers
Dietary change could be a key to enhancing colon cancer treatment
Albendazole – Dual inhibition of glucose uptake and energy supply synergistically restrains the growth and metastasis of breast cancer
https://www.sciencedirect.com/science/article/abs/pii/S1001841722007306
Albendazole – PD-L1-Targeted Co-Delivery of Two Chemotherapeutics for Efficient Suppression of Skin Cancer Growth
https://www.mdpi.com/1999-4923/14/7/1488
Mebendazole – In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity
https://pubs.acs.org/doi/full/10.1021/acsomega.1c05519
Anthelmintic drug albendazole arrests human gastric cancer cells at the mitotic phase and induces apoptosis
https://www.spandidos-publications.com/etm/13/2/595
Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer
https://link.springer.com/article/10.1007/s00432-013-1539-5
Repositioning of Anthelmintic Drugs for the Treatment of Cancers of the Digestive System
https://www.mdpi.com/1422-0067/21/14/4957
Repurposing old drugs to fight multidrug resistant cancers
https://www.sciencedirect.com/science/article/abs/pii/S136876462030042X
Albendazole-induced autophagy blockade contributes to elevated apoptosis in cholangiocarcinoma cells through AMPK/mTOR activation
https://www.sciencedirect.com/science/article/abs/pii/S0041008X22003593
Anthelmintic Flubendazole and Its Potential Use in Anticancer Therapy
https://actamedica.lfhk.cuni.cz/60/1/0005/
Methionine-Restricted Diet a Promising Cancer Treatment
Research suggests that eating less of this common amino acid could starve tumors, keep them from growing
mRNA revolutionized the race for a Covid-19 vaccine. Could cancer be next?
Skipping Meals, Fasting and Eating Meals Too Closely Together May Be Linked to Increased Mortality Risk
The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids
The data in this manuscript indicate a crucial role for a single phosphorylation site on the regulatory beta subunit of AMPK to stimulate mitochondrial biogenesis and autophagy/mitophagy in response to increases in fatty acids. This suggests a potential unifying mechanism which may be important for mediating the beneficial effects of dietary interventions that increase free-fatty acid availability such as intermittent fasting and ketogenic diets.
https://www.pnas.org/doi/10.1073/pnas.2119824119
Common painkillers like ibuprofen and naproxen can make arthritis inflammation even worse
COVID-19 disrupts gut microbiome
https://www.nih.gov/news-events/nih-research-matters/covid-19-disrupts-gut-microbiome
Fungi detected in 35 cancer types, often intracellular
Myocarditis after COVID vaccination is rare but higher in younger males
Merck’s Keytruda Notches Another Win in Stomach Cancer
https://www.biospace.com/article/merck-s-keytruda-notches-another-win-in-stomach-cancer-/
The COVID-19 Omicron Variant
https://www.webmd.com/lung/covid-omicron-variant#2
Omicron variant BQ.1.1 found to be resistant to all monoclonal antibody treatments
https://medicalxpress.com/news/2022-11-omicron-variant-bq11-resistant-monoclonal.html
Risk for newly diagnosed diabetes after COVID-19: a systematic review and meta-analysis
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02656-y
The Cause of Alzheimer’s Could Be Coming From Inside Your Mouth
https://www.sciencealert.com/the-cause-of-alzheimers-could-be-coming-from-inside-your-mouth
Low to Moderate Stress Is Good for You
Remarkable Weight Loss – Study Finds New Benefits of a Plant-Based Diet
Remarkable Weight Loss – Study Finds New Benefits of a Plant-Based Diet
Dietary advanced glycation products and their associations with insulin sensitivity and body weight
https://onlinelibrary.wiley.com/doi/10.1002/osp4.646
Is aspirin a wonder pill or does it do more harm than good? It’s hailed for helping prevent heart attacks — and now potentially even cancer. But worrying reports also link it to fatal falls and a higher risk of internal bleeding
https://www.dailymail.co.uk/health/article-11453721/Is-aspirin-wonder-pill-does-harm-good.html
Low Protein Diet May Inhibit Colon Cancer Growth
Nicotinamide Riboside May Make Existing Cancer Worse
https://www.lifespan.io/news/nicotinamide-riboside-may-make-existing-cancer-worse/
Identification of a key ceRNA network associated with ferroptosis in gastric cancer
https://www.nature.com/articles/s41598-022-24402-3
FDA approves AstraZeneca’s Imfinzi, Imjudo for metastatic lung cancer
Drug triggers immune cells to attack prostate cancer
Compound kills tumors in mice, human cancer cells in multiple ways
Compound kills tumors in mice, human cancer cells in multiple ways
Metastatic triple negative breast cancer adapts its metabolism to destination tissues while retaining key metabolic signatures
https://www.pnas.org/doi/full/10.1073/pnas.2205456119
“Flower Power”: Controlled Inhalation of THC-Predominant Cannabis Flos Improves Health-Related Quality of Life and Symptoms of Chronic Pain and Anxiety
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599241/
Mars was covered by a 300-meter-deep ocean 4.5 billion years ago
Labor in Wuhan: Alarmglocken läuteten schon im Jahr 2019
Der Verdacht erhärtet sich: Ein Laborunfall hat die Corona-Pandemie ausgelöst.
Ivermectin inhibits tumor metastasis by regulating the Wnt/β-catenin/integrin β1/FAK signaling pathway.
https://europepmc.org/article/pmc/pmc9641399
Is this what’s causing long Covid? Brain scans of patients with lingering symptoms show clusters of plaques in areas responsible for tiredness, headaches and cognition
- Researchers found that Covid sufferers may experience changes to their brain
- MRIs revealed that those infected experienced plaque in their brain
- Changes to the brain were observed in parts responsible for the symptoms
- This is the first study to reveal the direct impact Covid could have on the brain
Scientists Reveal Key Differences in Immune Response to Inactivated Virus and mRNA COVID-19 Vaccines
Scientists Reveal Key Differences in Immune Response to Inactivated Virus and mRNA COVID-19 Vaccines
Study shows miraculous health benefits of honey
https://www.geo.tv/latest/453440-study-shows-miraculous-health-benefits-of-honey
Colon cancer: Dying cancer cells give neighboring tumor cells instructions on how to survive
https://www.sciencedaily.com/releases/2022/11/221117135550.htm