Articles and science papers (unsorted part 2.8)

Curcumin inhibits spike protein of new SARS-CoV-2 variant of concern (VOC) Omicron

https://www.sciencedirect.com/science/article/pii/S0010482522003444

Ceylon cinnamon and its major compound Cinnamaldehyde can limit overshooting inflammatory signaling and angiogenesis in vitro: implications for COVID-19 treatment

https://www.biorxiv.org/content/10.1101/2021.06.16.448642v1.abstract

The Original Antigenic Sin: How the vaccines might be making COVID-19 worse

https://www.lifesitenews.com/opinion/the-original-antigenic-sin-how-the-vaccines-might-be-making-covid-19-worse/

Follow Your Nose: A Key Clue to Understanding and Treating COVID-19

https://www.frontiersin.org/articles/10.3389/fendo.2021.747744/full

Novel Immune Cell Population May Trigger Inflammation in Multiple Sclerosis and Other Brain Disorders

Getting exposed to another coronavirus can help you fight COVID-19, study says

https://www.deseret.com/coronavirus/2021/11/27/22798426/coronavirus-exposure-fight-covid-19-study

Cancer cells resist chemotherapy by helping their neighbors cheat death

https://medicalxpress.com/news/2021-11-cancer-cells-resist-chemotherapy-neighbors.html

Research Says GABA Supplement Is Also a Good Sleep Aid

https://www.cnet.com/health/sleep/goodbye-melatonin-research-says-this-dietary-supplement-is-also-a-good-sleep-aid/

B3 – Popular ‘anti-aging’ supplement may lead to brain cancer

B3 – Popular ‘anti-aging’ supplement may lead to brain cancer

Vaccine shown to prolong life of patients with aggressive brain cancer

Trial results suggest people with newly diagnosed glioblastoma could potentially be given extra years of life

https://www.theguardian.com/science/2022/nov/17/vaccine-shown-to-prolong-life-patients-aggressive-brain-cancer-trial-glioblastoma

Unusual Type of Antibody Shows Ultrapotent Activity Against Zika

https://news.weill.cornell.edu/news/2022/11/unusual-type-of-antibody-shows-ultrapotent-activity-against-zika

Acute and postacute sequelae associated with SARS-CoV-2 reinfection

https://www.nature.com/articles/s41591-022-02051-3

Novel cancer-killing drug type harnesses the immune system

https://www.pnas.org/post/journal-club/cancer-killing-drug-strategy-harnesses-immune-system

Intravenous delivery may improve nanoparticle vaccine efficacy

https://www.medicalnewstoday.com/articles/cancer-intravenous-delivery-may-improve-nanoparticle-vaccine-efficacy

2 diseases, one drug: How a drug for deadly cancer could treat COVID-19

https://www.fiercebiotech.com/research/two-diseases-one-drug-how-drug-deadly-cancer-could-treat-covid-19

Targeting GRP78 suppresses oncogenic KRAS protein expression and reduces viability of cancer cells bearing various KRAS mutations

https://www.sciencedirect.com/science/article/pii/S147655862200063X

Chinese Herbal Medicine Can Significantly Improve Anti-Cancer Treatment

https://www.theepochtimes.com/chinese-herbal-medicine-can-significantly-improve-anti-cancer-treatment-korean-doctors_4698468.html

Bojungikki-Tang Improves Response to PD-L1 Immunotherapy by Regulating the Tumor Microenvironment in MC38 Tumor-Bearing Mice

https://www.frontiersin.org/articles/10.3389/fphar.2022.901563/full

Chinese Red Dates: An Ancient Cancer Fighter

This delicious superfood has a long history in Chinese medicine

https://www.theepochtimes.com/health/chinese-red-dates-an-ancient-cancer-fighter_4636650.html

Triterpenoids from Ziziphus jujuba induce apoptotic cell death in human cancer cells through mitochondrial reactive oxygen species production

https://pubs.rsc.org/en/content/articlelanding/2018/fo/c8fo00526e

https://www.ebay.de/itm/284790015687

Ancient Chinese medicine unlocks new possibilities for cancer treatment

After 20 years of research, Yale pharmacologist Yung-Chi Cheng and his partners are launching the first international clinical trial for a botanical drug.

licorice, skullcap, peony, and dates

The botanical drug YIV-906 (center) is developed from an 1800-year-old Chinese formula and relies on four naturally derived ingredients: licorice, skullcap, peony, and dates.

https://news.yale.edu/2020/03/13/ancient-chinese-medicine-unlocks-new-possibilities-cancer-treatment

Cancer Drug Derived From Himalayan ‘Caterpillar Fungus’ Smashes Early Clinical Trial

https://www.sciencealert.com/himalayan-fungus-drug-currently-in-human-trials-shown-to-be-potent-cancer-killer

Metabolic Reprogramming of Chemoresistant Cancer Cells and the Potential Significance of Metabolic Regulation in the Reversal of Cancer Chemoresistance

https://www.mdpi.com/2218-1989/10/7/289

The exercise pill: How exercise keeps your brain healthy and protects it against depression and anxiety

https://theconversation.com/the-exercise-pill-how-exercise-keeps-your-brain-healthy-and-protects-it-against-depression-and-anxiety-155848

CAR-T Therapy May Treat Conditions Other Than Blood Cancers, Research Shows

https://www.verywellhealth.com/car-t-treatment-whats-next-6830735

Understanding the types of leukemia

https://www.mdanderson.org/cancerwise/what-are-the-types-of-leukemia–5-things-to-know.h00-159542112.html

Common and rare types of blood cancer

https://www.medicalnewstoday.com/articles/types-of-blood-cancer

Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

https://www.cell.com/cancer-cell/fulltext/S1535-6108(22)00378-6

letrozole – Could a repurposed drug break a centurylong stalemate in the war on cancer?

https://radiologybusiness.com/topics/clinical/clinical-research/could-repurposed-drug-break-centurylong-stalemate-war-cancer

Chloroquine induces transitory attenuation of proliferation of human lung cancer cells through regulation of mutant P53 and YAP

https://link.springer.com/article/10.1007/s11033-022-08072-y

Antitumor Activity of Simvastatin in Preclinical Models of Mantle Cell Lymphoma

https://www.mdpi.com/2072-6694/14/22/5601

Statins inhibit proliferation and induce apoptosis in triple-negative breast cancer cells

https://link.springer.com/article/10.1007/s12032-022-01733-9

Repurposed Itraconazole for use in the treatment of malignancies as a promising therapeutic strategy

https://www.sciencedirect.com/science/article/pii/S0753332222010058

Repurposing antifungal drugs for cancer therapy

https://www.sciencedirect.com/science/article/pii/S2090123222001990

Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner

https://synapse.koreamed.org/articles/1516079962

Anti-cancer effects of fenbendazole on 5-fluorouracil-resistant colorectal cancer cells

https://synapse.koreamed.org/articles/1516079963

Cancer Neuroscience: Evidence for a New Hallmark of Cancer

https://onlinelibrary.wiley.com/doi/full/10.1002/adbi.202200192

Repurposing of metabolic drugs and mitochondrial modulators as an emerging class of cancer therapeutics with a special focus on breast cancer

https://www.sciencedirect.com/science/article/pii/S2667394022000399

GABAergic signaling beyond synapses: an emerging target for cancer therapy

https://www.sciencedirect.com/science/article/abs/pii/S0962892422001957

Disulfiram loaded calcium phosphate nanoparticles for enhanced cancer immunotherapy

https://www.sciencedirect.com/science/article/abs/pii/S0142961222005208

Metabolic reprogramming in high-grade sarcomas: repurposing anti-cholesterol agents as a novel therapeutic strategy

https://aacrjournals.org/clincancerres/article/28/18_Supplement/B014/708884

The effect of flubendazole on microtubule polymerization and post-translational modifications

https://www.annalsofoncology.org/article/S0923-7534(22)04079-0/fulltext

Antidepressant Drug Sertraline against Human Cancer Cells

https://www.mdpi.com/2218-273X/12/10/1513

Metformin and bladder cancer: Drug repurposing as a potential tool for novel therapy

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666131/

Statins as Repurposed Drugs in Gynecological Cancer

https://www.mdpi.com/1422-0067/23/22/13937

Clinically Relevant Statin-drug Combinations to Potentiate Breast Cancer Cell Death

https://tspace.library.utoronto.ca/handle/1807/125148

Venetoclax – Targeting notch signaling pathway in breast cancer stem cells through drug repurposing approach

https://link.springer.com/article/10.1007/s11030-022-10561-y

Novel molecular imaging radiotracer can precisely diagnose multiple cancers

https://www.news-medical.net/news/20221120/Novel-molecular-imaging-radiotracer-can-precisely-diagnose-multiple-cancers.aspx

Dietary change could be a key to enhancing colon cancer treatment

https://www.news-medical.net/news/20221120/Dietary-change-could-be-a-key-to-enhancing-colon-cancer-treatment.aspx

Albendazole – Dual inhibition of glucose uptake and energy supply synergistically restrains the growth and metastasis of breast cancer

https://www.sciencedirect.com/science/article/abs/pii/S1001841722007306

Albendazole – PD-L1-Targeted Co-Delivery of Two Chemotherapeutics for Efficient Suppression of Skin Cancer Growth

https://www.mdpi.com/1999-4923/14/7/1488

Mebendazole – In Silico and In Vitro Studies for Benzimidazole Anthelmintics Repurposing as VEGFR-2 Antagonists: Novel Mebendazole-Loaded Mixed Micelles with Enhanced Dissolution and Anticancer Activity

https://pubs.acs.org/doi/full/10.1021/acsomega.1c05519

Anthelmintic drug albendazole arrests human gastric cancer cells at the mitotic phase and induces apoptosis

https://www.spandidos-publications.com/etm/13/2/595

Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer

https://link.springer.com/article/10.1007/s00432-013-1539-5

Repositioning of Anthelmintic Drugs for the Treatment of Cancers of the Digestive System

https://www.mdpi.com/1422-0067/21/14/4957

Repurposing old drugs to fight multidrug resistant cancers

https://www.sciencedirect.com/science/article/abs/pii/S136876462030042X

Albendazole-induced autophagy blockade contributes to elevated apoptosis in cholangiocarcinoma cells through AMPK/mTOR activation

https://www.sciencedirect.com/science/article/abs/pii/S0041008X22003593

Anthelmintic Flubendazole and Its Potential Use in Anticancer Therapy

https://actamedica.lfhk.cuni.cz/60/1/0005/

Methionine-Restricted Diet a Promising Cancer Treatment

Research suggests that eating less of this common amino acid could starve tumors, keep them from growing

https://www.theepochtimes.com/health/methionine-restricted-diet-a-promising-cancer-treatment_4860753.html

mRNA revolutionized the race for a Covid-19 vaccine. Could cancer be next?

Skipping Meals, Fasting and Eating Meals Too Closely Together May Be Linked to Increased Mortality Risk

The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids

The data in this manuscript indicate a crucial role for a single phosphorylation site on the regulatory beta subunit of AMPK to stimulate mitochondrial biogenesis and autophagy/mitophagy in response to increases in fatty acids. This suggests a potential unifying mechanism which may be important for mediating the beneficial effects of dietary interventions that increase free-fatty acid availability such as intermittent fasting and ketogenic diets.

https://www.pnas.org/doi/10.1073/pnas.2119824119

Common painkillers like ibuprofen and naproxen can make arthritis inflammation even worse

COVID-19 disrupts gut microbiome

https://www.nih.gov/news-events/nih-research-matters/covid-19-disrupts-gut-microbiome

Fungi detected in 35 cancer types, often intracellular

https://www.news-medical.net/news/20221122/Fungi-detected-in-35-cancer-types-often-intracellular.aspx

Myocarditis after COVID vaccination is rare but higher in younger males

https://www.news-medical.net/news/20221122/Myocarditis-after-COVID-vaccination-is-rare-but-higher-in-younger-males.aspx

Merck’s Keytruda Notches Another Win in Stomach Cancer

https://www.biospace.com/article/merck-s-keytruda-notches-another-win-in-stomach-cancer-/

The COVID-19 Omicron Variant

https://www.webmd.com/lung/covid-omicron-variant#2

Omicron variant BQ.1.1 found to be resistant to all monoclonal antibody treatments

https://medicalxpress.com/news/2022-11-omicron-variant-bq11-resistant-monoclonal.html

Risk for newly diagnosed diabetes after COVID-19: a systematic review and meta-analysis

https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-022-02656-y

The Cause of Alzheimer’s Could Be Coming From Inside Your Mouth

https://www.sciencealert.com/the-cause-of-alzheimers-could-be-coming-from-inside-your-mouth

Low to Moderate Stress Is Good for You

Remarkable Weight Loss – Study Finds New Benefits of a Plant-Based Diet

Remarkable Weight Loss – Study Finds New Benefits of a Plant-Based Diet

Dietary advanced glycation products and their associations with insulin sensitivity and body weight

https://onlinelibrary.wiley.com/doi/10.1002/osp4.646

Is aspirin a wonder pill or does it do more harm than good? It’s hailed for helping prevent heart attacks — and now potentially even cancer. But worrying reports also link it to fatal falls and a higher risk of internal bleeding

https://www.dailymail.co.uk/health/article-11453721/Is-aspirin-wonder-pill-does-harm-good.html

Low Protein Diet May Inhibit Colon Cancer Growth

Nicotinamide Riboside May Make Existing Cancer Worse

https://www.lifespan.io/news/nicotinamide-riboside-may-make-existing-cancer-worse/

Identification of a key ceRNA network associated with ferroptosis in gastric cancer

https://www.nature.com/articles/s41598-022-24402-3

FDA approves AstraZeneca’s Imfinzi, Imjudo for metastatic lung cancer

https://www.medicalnewstoday.com/articles/fda-approves-astrazenecas-imfinzi-imjudo-for-metastatic-lung-cancer

Drug triggers immune cells to attack prostate cancer

Compound kills tumors in mice, human cancer cells in multiple ways

Compound kills tumors in mice, human cancer cells in multiple ways

Metastatic triple negative breast cancer adapts its metabolism to destination tissues while retaining key metabolic signatures

https://www.pnas.org/doi/full/10.1073/pnas.2205456119

Flower Power”: Controlled Inhalation of THC-Predominant Cannabis Flos Improves Health-Related Quality of Life and Symptoms of Chronic Pain and Anxiety

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599241/

Mars was covered by a 300-meter-deep ocean 4.5 billion years ago

Labor in Wuhan: Alarmglocken läuteten schon im Jahr 2019

Der Verdacht erhärtet sich: Ein Laborunfall hat die Corona-Pandemie ausgelöst.

Ivermectin inhibits tumor metastasis by regulating the Wnt/β-catenin/integrin β1/FAK signaling pathway.

https://europepmc.org/article/pmc/pmc9641399

Is this what’s causing long Covid? Brain scans of patients with lingering symptoms show clusters of plaques in areas responsible for tiredness, headaches and cognition

  • Researchers found that Covid sufferers may experience changes to their brain
  • MRIs revealed that those infected experienced plaque in their brain
  • Changes to the brain were observed in parts responsible for the symptoms
  • This is the first study to reveal the direct impact Covid could have on the brain

https://www.dailymail.co.uk/health/article-11452981/MRIs-Covid-patients-clusters-plaques-areas-responsible-tiredness-anxiety.html

Scientists Reveal Key Differences in Immune Response to Inactivated Virus and mRNA COVID-19 Vaccines

Scientists Reveal Key Differences in Immune Response to Inactivated Virus and mRNA COVID-19 Vaccines

Study shows miraculous health benefits of honey

https://www.geo.tv/latest/453440-study-shows-miraculous-health-benefits-of-honey

Colon cancer: Dying cancer cells give neighboring tumor cells instructions on how to survive

https://www.sciencedaily.com/releases/2022/11/221117135550.htm