Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182444/
Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression-associated genes in locally advanced pancreatic cancer
https://aacrjournals.org/cancerres/article/82/22_Supplement/C043/710344
Effects of losartan and vitamin D on outcomes in metastatic pancreatic adenocarcinoma
https://ascopubs.org/doi/abs/10.1200/JCO.2023.41.4_suppl.723
Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer
Is it still worth pursuing the repurposing of metformin as a cancer therapeutic?
https://www.nature.com/articles/s41416-023-02204-2
‘Dead zone’ within tumor promotes cancer spread, helped by a protein secreted by cancer cells
https://medicalxpress.com/news/2023-02-dead-zone-tumor-cancer-protein.html
Lancet study reveals natural immunity is just as effective as COVID vaccine
Lab Leak Most Likely Origin of Covid-19 Pandemic, Energy Department Now Says
U.S. agency’s revised assessment is based on new intelligence
https://www.wsj.com/articles/covid-origin-china-lab-leak-807b7b0a
Berberine promotes IGF2BP3 ubiquitination by TRIM21 to induce G1/S phase arrest in colorectal cancer cells
https://www.sciencedirect.com/science/article/abs/pii/S0009279723000753
Intermittent fasting could increase risk of cancer, research finds
The findings could lead to a better understanding of how chronic fasting may affect the body in the long term
https://www.independent.co.uk/news/science/cancer-intermittent-fasting-health-risk-b2290767.html
Meet the $10,000 Nvidia chip powering the race for A.I.
https://www.cnbc.com/2023/02/23/nvidias-a100-is-the-10000-chip-powering-the-race-for-ai-.html
Luteolin – Potential of bioactive compound of Cyperus rotundus L. rhizome extract as inhibitor of PD-L1/PD-1 interaction
https://li01.tci-thaijo.org/index.php/anres/article/view/256137
Icariside II potentiates the anti-PD-1 antitumor effect by reducing chemotactic infiltration of myeloid-derived suppressor cells into the tumor microenvironment via ROS-mediated inactivation of the SRC/ERK/STAT3 signaling pathways
https://www.sciencedirect.com/science/article/abs/pii/S0944711322007255
Inflammation is culprit behind long COVID, study suggests
Murine research indicates that the S1 protein is gatekeeper for how the SARS-CoV-2 virus crosses the blood-brain barrier.
https://newsroom.uw.edu/postscript/inflammation-culprit-behind-long-covid-study-suggests
Ivermectin – Doctors Bristle At New FDA Authority To Ban Off-Label Uses For Drugs
https://www.zerohedge.com/medical/doctors-bristle-new-fda-authority-ban-label-uses-drugs
Comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines
https://medicalxpress.com/news/2023-02-reveals-covid-vaccine-blood-clot.html
Incident autoimmune diseases in association with a SARS-CoV-2 infection
https://www.medrxiv.org/content/10.1101/2023.01.25.23285014v1
How can the size of Universe be bigger than its age?
How is the Universe so big, and why does its size seem to be bigger than its age?

https://www.skyatnightmagazine.com/space-science/size-of-universe-bigger-than-age/
The scale of the entire Universe versus JWST’s views
The glorious sights that JWST keeps revealing are less than a millionth of the whole Universe. Just imagine what else is out there.
https://bigthink.com/starts-with-a-bang/jwst-universe/
Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity
https://www.aging-us.com/article/204498/text
In Massive Galactic Discovery, Webb Spots Super Old Galaxies That Shouldn’t Exist
In Massive Galactic Discovery, Webb Spots Super Old Galaxies That Shouldn’t Exist
Florida Surgeon General Warns Life-Threatening VAERS Reports Up 4,400 Percent Since COVID-19 Vaccine Rollout
Novavax COVID-19 Vaccine Associated With Heart Inflammation
https://www.zerohedge.com/covid-19/novavax-covid-19-vaccine-associated-heart-inflammation-study
Role of Glutathione in Cancer: From Mechanisms to Therapies
https://www.mdpi.com/2218-273X/10/10/1429
Xylitol acts as an anticancer monosaccharide to induce selective cancer death via regulation of the glutathione level
https://www.sciencedirect.com/science/article/pii/S0009279720301381
Biological and Pharmacological Potential of Xylitol: A Molecular Insight of Unique Metabolism
https://www.mdpi.com/2304-8158/9/11/1592
Biological mechanisms underpinning the development of Long COVID
https://doi.org/10.1016/j.isci.2023.106935
Cytotoxic Activity, Anti-Migration and In Silico Study of Black Ginger (Kaempferia parviflora) Extract against Breast Cancer Cell
https://doi.org/10.3390/cancers15102785
Recovery of the Sensitivity to Anti-PD-1 Antibody by Celecoxib in Lung Cancer
https://ar.iiarjournals.org/content/40/9/5309.long
Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion
Targeting Cancer Stem Cells as the Key Driver of Carcinogenesis and Therapeutic Resistance
https://www.mdpi.com/1422-0067/24/2/1786
Breast cancer prevention with liquiritigenin from licorice
https://doi.org/10.1038/s41598-023-34762-z
Endothelial dysfunction and angiogenesis: what is missing from COVID-19 and cannabidiol story?
https://doi.org/10.1186/s42238-022-00129-w
PD-1 blockade following isolated limb perfusion with vaccinia virus prevents local and distant relapse of soft-tissue sarcoma
How T cells could fight many coronaviruses at once
LJI researchers work to head off future pandemics by uncovering key similarities between SARS-CoV-2 and common cold coronaviruses
Novel approach improves the efficacy of immune checkpoint blockade and minimizes related side effects
Fish evolution takes place in decades – not millions of years
https://www.earth.com/news/fish-evolution-takes-place-in-decades-not-millions-of-years/
Geneticists discover hidden ‘whole genome duplication’ that may explain why some species survived mass extinctions
https://phys.org/news/2023-05-geneticists-hidden-genome-duplication-species.html
Study examines how DNA damage is repaired by antioxidant enzymes
https://phys.org/news/2023-05-dna-antioxidant-enzymes.html
Study sheds light on metabolic enzymes and processes essential for DNA damage repair
Atlantic hurricane season 2023: El Niño and extreme Atlantic Ocean heat are about to clash
Essential process for SARS-CoV-2 viral replication visualized
https://phys.org/news/2023-05-essential-sars-cov-viral-replication-visualized.html
Fungal–Bacterial Co-Infections and Super-Infections among Hospitalized COVID-19 Patients
https://www.mdpi.com/2309-608X/9/6/598
Nvidia building one of the world’s fastest generative AI supercomputers in Israel
The Israel-1 supercomputer was developed in Israel over the past 18 months at a cost of hundreds of millions of dollars
https://www.calcalistech.com/ctechnews/article/ryfcv6zl3
Gene Elimination in Tregs Triggers Lifelong Anticancer Response in Mice
Pentoxifylline changes the balance of immune cell population in breast tumor-infiltrating lymphocytes
https://link.springer.com/article/10.1007/s12032-023-02034-5
Immunotherapy: A promising novel endometriosis therapy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10150018/
NF-κB in control of regulatory T cell development, identity, and function
https://link.springer.com/article/10.1007/s00109-022-02215-1
Artesunate targets cellular metabolism to regulate the Th17/Treg cell balance
https://link.springer.com/article/10.1007/s00011-023-01729-9
Glycyrrhizic acid facilitates anti-tumor immunity by attenuating Tregs and MDSCs: An immunotherapeutic approach
https://www.sciencedirect.com/science/article/abs/pii/S1567576920310456
NF-κB in the New Era of Cancer Therapy
https://www.sciencedirect.com/science/article/abs/pii/S2405803320301333
Treg programming and therapeutic reprogramming in cancer
https://onlinelibrary.wiley.com/doi/full/10.1111/imm.13058
NF-κB c-Rel Is Crucial for the Regulatory T Cell Immune Checkpoint in Cancer
https://www.sciencedirect.com/science/article/pii/S0092867417308929
The reversal of aging begins in your gut: New study reveals promising findings
https://interestingengineering.com/health/reversal-of-aging-begins-in-gut
Cannabidiol alters mitochondrial bioenergetics via VDAC1 and triggers cell death in hormone-refractory prostate cancer
https://www.sciencedirect.com/science/article/pii/S1043661823000397
RNA’s ‘joints’ play key role in our gene expression, scientists find
https://phys.org/news/2023-02-rna-joints-play-key-role.html
The Universe violates the perfect cosmological principle
https://bigthink.com/starts-with-a-bang/perfect-cosmological-principle/
Scientists find that fish can recognize themselves in photos – study
Humans readily distinguish between photographs of both familiar – including the self – and unknown people by referring to mental images of faces. But what about fish?
https://www.jpost.com/science/article-731365
Extracts From Two Wild Plants Inhibit COVID-19 Virus
Two common wild plants contain extracts that inhibit the ability of the virus that causes COVID-19 to infect living cells
Tall goldenrod and eagle fern. Both plant species are native to North America and are known for traditional medicinal uses by Native Americans.
How do we know the timeline of our Universe?
From the earliest stages of the hot Big Bang (and even before) to our dark energy-dominated present, how and when did the Universe grow up?
https://bigthink.com/starts-with-a-bang/timeline-of-our-universe/
An Unintended Consequence of Antidepressant Use May be Antibiotic Resistance
Discovery of T-cells that protect against deadly pneumococcal disease
How immortal jellyfish turn back time
https://theconversation.com/how-immortal-jellyfish-turn-back-time-197304
New treatment approach for prostate cancer could stop resistance in its tracks
https://medicalxpress.com/news/2023-02-treatment-approach-prostate-cancer-resistance.html
Tricaprin – “Remarkable” Results – Scientists Discover That a Dietary Supplement Could Fix a Broken Heart
“Remarkable” Results – Scientists Discover That a Dietary Supplement Could Fix a Broken Heart
Intermittent fasting spurs proliferation of liver cells in lab mice, study finds
https://phys.org/news/2023-02-intermittent-fasting-spurs-proliferation-liver.html
Team identifies a nutrient that cancer cells crave
Arginine is an amino acid naturally produced by our bodies and plentiful in the fish, meat, and nuts that we eat. But as recent research in Science Advances reveals, arginine is an essential nutrient for cancer cells too. And starving them of it could potentially render tumors more vulnerable to the body’s natural immune response.
https://phys.org/news/2023-02-team-nutrient-cancer-cells-crave.html
Some cancer cells grow stronger after chemo. Research hints at how to kill them
Stopping the cancer cells that thrive on chemotherapy – research into how pancreatic tumors adapt to stress could lead to a new treatment approach
How Parkinson’s Disease Affects the Endocannabinoid System
Obesity-Associated Neurodegeneration Pattern Mimics Alzheimer’s Disease
https://content.iospress.com/articles/journal-of-alzheimers-disease/jad220535
Repurposing Ponatinib as a PD-L1 Inhibitor Revealed by Drug Repurposing Screening and Validation by In Vitro and In Vivo Experiments
https://pubs.acs.org/doi/pdf/10.1021/acsptsci.2c00214
Breast cancer and neurotransmitters: emerging insights on mechanisms and therapeutic directions
https://www.nature.com/articles/s41388-022-02584-4
Effect of metformin on outcomes of patients treated with immune checkpoint inhibitors: a retrospective cohort study
The use of metformin is associated with survival benefits in patients undergoing immunotherapy.
https://link.springer.com/article/10.1007/s00262-022-03363-6
The Cause of Depression Is Probably Not What You Think
https://www.quantamagazine.org/the-cause-of-depression-is-probably-not-what-you-think-20230126/
Vitamin C enhances NF-κB-driven epigenomic reprogramming and boosts the immunogenic properties of dendritic cells
https://academic.oup.com/nar/article/50/19/10981/6777795
Long COVID: major findings, mechanisms and recommendations
https://www.nature.com/articles/s41579-022-00846-2
Revenge is sweet: Experts hope toxin found in SUGAR cane will turn tide on drug-resistant superbugs — calling it the ‘most promising antibiotic in decades’
- Albicidin is an antibiotic made by disease-causing pathogen in sugar cane leaves
- Scientists have discovered the molecule blocks infection by changing its shape
- New tests showed it is effective against salmonella, E. coli and pneumonia
Effectiveness of Vaccination and Previous Infection Against Omicron Infection and Severe Outcomes in Children Under 12 Years of Age
https://www.medrxiv.org/content/10.1101/2023.01.18.23284739v1.full
Immunotherapy with two novel drugs shows activity in colorectal cancer
An Old TB Vaccine Might Help Stave Off Diabetes, Cancer Alzheimer’s, and More
The BCG vaccine might assist in preventing a range of major diseases
The sooner you expose a baby to a second language, the smarter they’ll be
Just hearing two languages helps babies develop cognitive skills before they even speak. Here’s how – and how you can help them develop those skills.
Harnessing the healing power within our cells
University of Queensland researchers have identified a pathway in cells that could be used to reprogram the body’s immune system to fight back against both chronic inflammatory and infectious diseases.
https://phys.org/news/2023-01-harnessing-power-cells.html
Scientists detail major mechanism lung cancers use to evade immune attack
COVID Vaccines Are “Obviously Dangerous” And Should Be Halted Immediately, Say Senior Swedish Doctors
Multiple sclerosis (MS): Intestinal bacteria may have an anti-inflammatory effect
https://www.medicalnewstoday.com/articles/multiple-sclerosis-gut-bacteria-anti-inflammatory-effects
Is the Triggering of PD-L1 Dimerization a Potential Mechanism for Food-Derived Small Molecules in Cancer Immunotherapy? A Study by Molecular Dynamics
https://www.mdpi.com/1422-0067/24/2/1413
Natural Active Ingredients and TRPV1 Modulation: Focus on Key Chemical Moieties Involved in Ligand–Target Interaction
https://www.mdpi.com/2223-7747/12/2/339
Emerging Perspectives on the Antiparasitic Mebendazole as a Repurposed Drug for the Treatment of Brain Cancers
https://www.mdpi.com/1422-0067/24/2/1334
Loss of Epigenetic Information Can Drive Aging, Restoration Can Reverse It
43% of people with COVID-19 get ‘long COVID’
SARS-CoV-2 escape from cytotoxic T cells during long-term COVID-19
https://www.nature.com/articles/s41467-022-34033-x
3-drug combo leads to ‘unprecedented’ response in pancreatic cancer models
Scientists Detail Major Mechanism Lung Cancers Use to Evade Immune Attack
Popular spice duo may ‘significantly’ lower blood sugar levels when combined – 30% drop
Cinnamon, Fenugreek or their combination
https://www.express.co.uk/life-style/health/1719275/diabetes-spice-cinnamon-fenugreek-blood-sugar
COVID-19 is more widespread in animals than we thought
From lions and tigers to big hairy armadillos, a growing number of animals have been infected with the coronavirus. Here’s what we’ve learned.
https://www.nationalgeographic.com/animals/article/how-so-many-animal-species-contract-covid
The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes
The researchers argue hepatocytes are susceptible to SARS-CoV-2 pseudovirus infection and propose that metformin could be a therapeutic option to attenuate SARS-CoV-2 infection in patients with fatty liver.
The spike of SARS-CoV-2 promotes metabolic rewiring in hepatocytes
Infectiousness of SARS-CoV-2 breakthrough infections and reinfections during the Omicron wave
https://www.nature.com/articles/s41591-022-02138-x
How COVID Vaccines Cause Cancer
https://www.theepochtimes.com/health/how-covid-vaccines-cause-cancer_4952911.html
Lung cancer pill cuts risk of death by half, says ‘thrilling’ study
Taking the drug osimertinib once a day after surgery reduces chance of patients dying by 51%, trials show
El Niño could return in 2023; what that means for the world’s weather
Scientists have found a way to make brain cancer cells die of stress
Aggressive glioblastoma tumours could be in trouble: a breakthrough discovery successfully wiped out cancer cells in mice. Researchers have developed a method that could cause cancerous cells to die of stress.
Beware the Splice of Life: This Killer Protein Causes Pancreatic Cancer
Researchers at the Cold Spring Harbor Laboratory found that the protein SRSF1, which regulates RNA splicing, plays a critical role in the development of pancreatic ductal adenocarcinoma (PDAC), a deadly form of pancreatic cancer. Elevated levels of SRSF1 lead to inflammation and stimulate tumor growth, while restoring normal levels halts the disease’s progress.
Beware the Splice of Life: This Killer Protein Causes Pancreatic Cancer
It Took Researchers Decades to Figure Out This Ancient Device “Too Advanced to be Real”
These microbes found in tumors promote cancer. What if we just kill them?
New studies show that bacteria help cancer cells evade the body’s immune response. Experts say this relationship could prove vital for wiping out cancer.
‘Tipping the balance’ of immune cells from bad to good reverses multiple sclerosis symptoms in mice
https://medicalxpress.com/news/2023-06-immune-cells-bad-good-reverses.html
Canadian researchers find brain inflammation in patients with long COVID
Warming climate could turn ocean plankton microbes into carbon emitters
https://phys.org/news/2023-05-climate-ocean-plankton-microbes-carbon.html
Novel approach improves the efficacy of immune checkpoint blockade and minimizes related side effects
Anti-cancer effects of fenbendazole on 5-fluorouracil-resistant colorectal cancer cells
https://doi.org/10.4196/kjpp.2022.26.5.377
Drug Repurposing to Enhance Antitumor Response to PD-1/PD-L1 Immune Checkpoint Inhibitors
https://doi.org/10.3390/cancers14143368
Repurposing of Benzimidazole Anthelmintic Drugs as Cancer Therapeutics
https://doi.org/10.3390/cancers14194601
Niclosamide is a potential candidate for the treatment of chemo-resistant osteosarcoma
https://doi.org/10.1590/1678-4685-GMB-2022-0136
Commiphora myrrh: a phytochemical and pharmacological update
https://doi.org/10.1007/s00210-022-02325-0
Cytotoxic Activity of Pineapple (Ananas comosus L.) Against Cancer Cells
https://doi.org/10.2991/978-94-6463-050-3_18
Niclosamide as a Promising Therapeutic Player in Human Cancer and Other Diseases
https://doi.org/10.3390/ijms232416116
Mebendazole prevents distant organ metastases in part by decreasing ITGβ4 expression and cancer stemness
https://doi.org/10.1186/s13058-022-01591-3
A Magic Remedy of Castor Oil
https://doi.org/10.35629/7781-0703775782
Anthelmintic Drugs as Emerging Immune Modulators in Cancer
https://doi.org/10.3390/ijms24076446
Drug Repurposing Flubendazole to Suppress Tumorigenicity via PCSK9-dependent Inhibition and Potentiate Lenvatinib Therapy for Hepatocellular Carcinoma
http://doi.org/10.7150/ijbs.81415
Benzimidazole carbamate induces cytotoxicity in breast cancer cells via two distinct cell death mechanisms
https://doi.org/10.1038/s41420-023-01454-6
Azithromycin, a potent autophagy inhibitor for cancer therapy, perturbs cytoskeletal protein dynamics
https://doi.org/10.1038/s41416-023-02210-4
Advancing Cancer Therapy with Copper/Disulfiram Nanomedicines and Drug Delivery Systems
https://doi.org/10.3390/pharmaceutics15061567
Drug Repurposing in Oncology: A Systematic Review of Randomized Controlled Clinical Trials
https://doi.org/10.3390/cancers15112972
Novel olive oil phenolic (−)-oleocanthal (+)-xylitol-based solid dispersion formulations with potent oral anti-breast cancer activities
https://doi.org/10.1016/j.ijpharm.2019.118596
Niacin / B3 – Taking Too Much of This Common Vitamin May Cause Vision Loss and Liver Damage
https://www.yahoo.com/lifestyle/taking-too-much-common-vitamin-112619630.html
Metformin – New study from UMN researchers says an existing drug is a promising treatment for long COVID
Metformin, a medication typically used as a treatment for Type 2 diabetes, has shown promise as an effective treatment for long COVID
Protection from metformin is even stronger among unvaccinated, women and younger adults, analysis shows.
Researchers visualize communication of G protein-coupled receptors, paving way for new drug discovery
https://phys.org/news/2023-06-visualize-communication-protein-coupled-receptors-paving.html
Octopuses Can Rewire Their ‘Brains’ by Editing Their Own RNA on The Fly
https://www.sciencealert.com/octopuses-can-rewire-their-brains-by-editing-their-own-rna-on-the-fly
Archaeologists Find Three Shipwrecks In the Mediterranean’s Treacherous Keith Reef
https://news.yahoo.com/archaeologists-three-shipwrecks-mediterraneans-treacherous-180000358.html
Universal redirection of CAR T cells against solid tumours via membrane-inserted ligands for the CAR
https://www.nature.com/articles/s41551-023-01048-8
Chinese quantum computer is 180 million times faster on AI-related tasks, says team led by ‘father of quantum’ Pan Jianwei
Jiuzhang computer took less than a second for a task that the fastest classical supercomputer in the world would take nearly five years to solve
NUCLEAR NOW movie
CLIMATE CHANGE:
THE EXISTENTIAL CRISIS
& CHALLENGE OF OUR TIME
Director Oliver Stone passionately presents the possibility of meeting the challenge through the power of nuclear energy.
https://www.nuclearnowfilm.com/
Instead of starving a cancer, researchers go after its defenses

Oxygen deprivation can propel tumor growth and spread
Researchers test drug combination as means to prevent drug resistance in cancer cells
Is Methylation Good or Bad?
https://www.spectracell.com/blog/posts/is-methylation-good-or-bad
Toxicological and pharmacokinetic properties of sucralose-6-acetate and its parent sucralose: in vitro screening assays
https://www.tandfonline.com/doi/full/10.1080/10937404.2023.2213903
Study Finds Sucralose Produces Previously Unidentified Metabolites
https://news.ncsu.edu/2018/08/sucralose-metabolites/
The systemic hallmarks of cancer
https://jcmtjournal.com/article/view/3625
Team discovers new organelle involved in cancer metastasis
https://scienceblog.com/521593/team-discovers-new-organelle-involved-in-cancer-metastasis/
PEA – Palmitoylethanolamide and hemp oil extract exert synergistic anti-nociceptive effects in mouse models of acute and chronic pain
https://www.sciencedirect.com/science/article/abs/pii/S1043661821001298
Ginger – 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137614
The Hallmarks of Cancer as Ecologically Driven Phenotypes
https://www.frontiersin.org/articles/10.3389/fevo.2021.661583/full
The Fascinating Effects of Baicalein on Cancer
https://www.mdpi.com/1422-0067/17/10/1681
New research discovers new cause of cancer coming from inside us
Australian cancer researchers have made an important new connection between a person’s cancer risk and the functions of circular RNAs, a recently discovered family of genetic fragments present within our cells.
https://medicalxpress.com/news/2023-06-cancer.html
Digestion of artificial sweetener sucralose appears to create metabolite that damages DNA
A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers
https://www.science.org/doi/10.1126/science.abo2296
Curcumin can suppress metastasis of colorectal cancer cells by activating a specific signaling pathway
Antihistamine Sparks Hope for Myelin Repair in Multiple Sclerosis
Augusta University researchers find potential lung cancer treatment in CBD
Engineered white blood cells can eliminate cancer
https://medicalxpress.com/news/2023-06-white-blood-cells-cancer.html
Bird Brains Can Sense Magnetic Fields With The Flick of a Switch
https://www.sciencealert.com/bird-brains-can-sense-magnetic-fields-with-the-flick-of-a-switch
Herpes Simplex Virus-1 in the Brain: The Dark Side of a Sneaky Infection
https://www.cell.com/trends/microbiology/fulltext/S0966-842X(20)30074-3
Research Finds Skipping Breakfast May Compromise the Immune System
Mount Sinai Research Finds Skipping Breakfast May Compromise the Immune System
Could your gut bacteria influence how intelligent you are?
People who are genetically predisposed to have higher levels of Fusicatenibacter bacteria scored better on verbal and mathematical tests, while those with more Oxalobacter scored lower
The Dual Role of the Natural Compound Cardamonin in Triple Negative Breast Cancer
Cardamonin from Cardamom seed spice – In conclusion, the results suggest that cardamonin may have a therapeutic potential to decrease the levels of PD-L1 in the tumor microenvironment combating the cancer cells’ effectiveness in evading the immune system.
https://jpet.aspetjournals.org/content/385/S3/493.abstract
The natural chalcone cardamonin selectively induces apoptosis in human neuroblastoma cells
https://www.sciencedirect.com/science/article/abs/pii/S0887233323000747
Study reveals how treatment-resistant prostate cancer provides its own hormonal fuel
Study reveals how treatment-resistant prostate cancer provides its own hormonal fuel
Repeated COVID-19 Vaccination Weakens Immune System
Not all benzimidazole derivatives are microtubule destabilizing agents
https://www.sciencedirect.com/science/article/pii/S0753332223007679
Modulating the tumor microenvironment improves antitumor effect of anti-PD-L1 mAb in breast cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182444/
In Situ Tumor Vaccine for Lymph Nodes Delivery and Cancer Therapy Based on Small Size Nanoadjuvant
https://onlinelibrary.wiley.com/doi/abs/10.1002/smll.202301041